Ya-Min Tian Selected Research

Enzymes

10/2019	Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates.
2/2013	Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.
4/2011	Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.
2/2011	Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions.
7/2006	Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation.
10/2004	Determination and comparison of specific activity of the HIF-prolyl hydroxylases.
7/2004	Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.
7/2002	Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Ya-Min Tian Research Topics

Disease

22	Hypoxia (Hypoxemia) 01/2023 - 07/2002
3	Neoplasms (Cancer) 05/2011 - 03/2009
2	Disease Progression 01/2023 - 10/2022
2	Anemia 02/2013 - 05/2011
2	Renal Cell Carcinoma (Grawitz Tumor) 02/2013 - 11/2009
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2023
1	Waldenstrom Macroglobulinemia (Macroglobulinemia) 10/2022
1	Osteochondroma (Osteocartilaginous Exostosis) 07/2021
1	Congenital Abnormalities (Deformity) 07/2021
1	Pain (Aches) 07/2021
1	Breast Neoplasms (Breast Cancer) 02/2014
1	Leukemia 10/2013
1	Ischemia 02/2013
1	Hepatocellular Carcinoma (Hepatoma) 02/2013

Drug/Important Bio-Agent (IBA)

16	Oxygen (Dioxygen)IBA 01/2023 - 07/2002
11	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2023 - 04/2003
8	EnzymesIBA 10/2019 - 07/2002
6	Transcription Factors (Transcription Factor)IBA 01/2016 - 08/2002
6	Mixed Function Oxygenases (Monooxygenases)IBA 02/2013 - 07/2002
3	OxygenasesIBA 05/2011 - 04/2011
2	orelabrutinibIBA 01/2023 - 10/2022
2	Protein Isoforms (Isoforms)IBA 01/2016 - 09/2004
2	Proteins (Proteins, Gene)FDA Link 04/2011 - 02/2011
2	Peptides (Polypeptides)IBA 02/2011 - 10/2004
1	Agammaglobulinaemia Tyrosine KinaseIBA 01/2023
1	DioxygenasesIBA 01/2023
1	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 01/2023
1	TriazolesIBA 01/2015
1	human MIRN4521 microRNAIBA 02/2014
1	Messenger RNA (mRNA)IBA 02/2014
1	DNA (Deoxyribonucleic Acid)IBA 02/2014
1	MicroRNAs (MicroRNA)IBA 02/2014
1	Glycyrrhizic Acid (Glycyrrhizin)IBA 10/2013
1	Phosphatidylcholines (Phosphatidylcholine)IBA 10/2013
1	Therapeutic UsesIBA 10/2013
1	S-Adenosylmethionine (Ademetionine)IBA 10/2013
1	Oxidants (Oxidizing Agents)IBA 03/2012
1	Lysine (L-Lysine)FDA Link 05/2011
1	Histones (Histone)IBA 05/2011
1	Cell ExtractsIBA 10/2004
1	Estrogens (Estrogen)FDA Link 09/2004
1	Hydralazine (Apresoline)FDA LinkGeneric 07/2004
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2004
1	dealanylalahopcinIBA 04/2003
1	ProcollagenIBA 04/2003
1	CobaltIBA 07/2002
1	AsparagineIBA 07/2002

Therapy/Procedure

1	Osteotomy 07/2021
1	Activities of Daily Living (ADL) 07/2021
1	Drug Therapy (Chemotherapy) 10/2013